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DNA-RNA

Nuleosyn offers an extensive line of standard phosphoramidites, RNA phosphoramidites, specialty amidites and modifiers, solid supports CPG, reagents and solvents for a wide variety of instruments

2'-DeoxyUridine phosphoramidite

CAS #
109389-30-2
Packing size
100µmol, 250mg
Synonyme(s)
dU
DeoxyuridineDeoxyribosePhosphoramiditeDNA & RNA SupportsDNA & RNA AnalogsDNA & RNA Nucleosides
2'-DeoxyUridine phosphoramidite Image 1

2'-DeoxyUridine phosphoramidite (dU) is an antibiotic that inhibits bacterial growth by binding to DNA, preventing transcription and replication. It has been shown to have antibacterial activity against a wide variety of bacteria, including staphylococcus, tuberculosis, and vibrio cholerae. dU is a chemotaxis regulator in the biosynthetic pathway of certain bacteria. These bacteria use this compound as a precursor for the production of other antibiotics. This antibiotic binds to the regulatory site on bacterial chemotaxis and inhibits the response to attractants such as sugars or amino acids.

Aspect
White solid
Purity
>95%
Solubility
Dichloromethane, EtOAc, MeCN
Molecular weight
730,80
Molecular formula

C39H47N4O8P

IUPAC
(2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

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