DNA-RNA
Nuleosyn offers an extensive line of standard phosphoramidites, RNA phosphoramidites, specialty amidites and modifiers, solid supports CPG, reagents and solvents for a wide variety of instruments
5'-Amino-Modifier C6 (C6-MMT)
CAS #
114616-27-2
Packing size
100µmol
5'-Amino-modifier C6 was designed to functionalize the 5'-terminus of the target oligonucleotide and to introduce a primary amino group into an oligo. After MMT deprotection, the amino group could be immediately conjugated with the activated carboxy group, and synthesize a stable amide linkage.
Aspect
Colorless oil
Purity
>95% (LC)
Solubility
Dichloromethane, EtOAc, MeCN
Molecular weight
589,76
Molecular formula
C35H48N3O3P
IUPAC
2-cyanoethyl (6-(((4-methoxyphenyl)diphenylmethyl)amino)hexyl) diisopropylphosphoramidite
K. D. Okochi et al., J. Org. Chem., 2017, 82, 10803-10811. read article
N. Tort et al., Bioconjugate Chem., 2012, 23, 11, 2183-2191. read article
A. E. Felber et al., Biomaterials, 2012, 33, 5955-5965. read article