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5'-Amino-Modifier C6 (C6-MMT)

CAS #

114616-27-2

Packing size

100µmol

Phosphoramidite DNA & RNA Supports

5'-Amino-modifier C6 was designed to functionalize the 5'-terminus of the target oligonucleotide and to introduce a primary amino group into an oligo. After MMT deprotection, the amino group could be immediately conjugated with the activated carboxy group, and synthesize a stable amide linkage.

Aspect

Colorless oil

Purity

>95% (LC)

Solubility

Dichloromethane, EtOAc, MeCN

Molecular weight

589,76

Molecular formula

C₃₅H₄₈N₃O₃P

IUPAC

2-cyanoethyl (6-(((4-methoxyphenyl)diphenylmethyl)amino)hexyl) diisopropylphosphoramidite

K. D. Okochi et al., J. Org. Chem., 2017, 82, 10803-10811. read article

N. Tort et al., Bioconjugate Chem., 2012, 23, 11, 2183-2191. read article

A. E. Felber et al., Biomaterials, 2012, 33, 5955-5965. read article

5'-Amino-Modifier C6 (C6-MMT)

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