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5'-Fluorescein phosphoramidite (6-FAM)

CAS #

204697-37-0

Packing size

100µmol, 250mg

Synonyme(s)

6-FAM

Fluorescein 5’-Amino-Modifier

Fluorescein is used extensively as a diagnostic tool, commonly used for labeling oligos and peptides. 5'-Fluorescein phosphoramidite contains no 4,4'-dimethoxytrityl (DMT) group and can be added only once at the 5'-terminus, thereby terminating synthesis.

Aspect

White solid

Purity

>95% (LC)

Solubility

Dichloromethane, EtOAc, MeCN

Molecular weight

843,95

Molecular formula

C₄₆H₅₈N₃O₁₀P

IUPAC

6-((6-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)hexyl)carbamoyl)-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl bis(2,2-dimethylpropanoate)

H-S. Kou et al., Microchimica Acta, 2023, 190, 375. read article

H. R. Kim, B. C. Kim, Analytica Chimica Acta, 2023, 1249, 340935. read article

A. Amani et al., Eur. J. Pharm. Sci., 2021, 167, 106007. read article

5'-Fluorescein phosphoramidite (6-FAM)

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