[13C,15N2]-5’-Deoxy-5-fluorouridine

5’-Deoxy-5-fluorouridine, also known as Doxifluridine, is a second-generation nucleoside analog prodrug used as a cytostatic agent in chemotherapy in several Asian countries. This antitumor agent is efficient in tumors, cell lines, or in fibroblasts transformed by H-ras or trk oncogenes. The most frequent adverse effects are neurotoxicity and mucositis.

Stable isotope labeled [¹³C,¹⁵N₂]-5’-Deoxy-5-fluorouridine is intended for use as an internal standard for the quantification of 5’-Deoxy-5-fluorouridine by LC or GC-mass spectrometry.