Stable isotope

Nucleosyn provides Custom Stable Isotope (²H, ¹³C, ¹⁵N) compounds to support projects dedicated to : Bioanalytics, Omics research, Molecular Imaging, and Biomarker discovery.

[13C2,15N4]-Decitabine

Packing size

5mg, 10mg, 25mg, bulk

Anticancer drug Therapeutic Drug Monitoring (TDM)

Decitabine is a cytidine analog used to treat myelodysplastic syndromes and acute myeloid leukemia. Common side effects include viral and bacterial infections, neutropenia, thrombopenia, and anemia.

Stable isotope labeled [¹³C₂,¹⁵N₄]-Decitabine is intended for use as an internal standard for the quantification of Decitabine by LC or GC-mass spectrometry.

Aspect

White powder

Purity

Chemical purity 95%; Isotopic Enrichment 98%

Solubility

DMSO, Water

Molecular weight

234.17

Molecular formula

C₆¹³C₂H₁₂¹⁵N₄O₄

IUPAC

4-(amino-15N)-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one-2,4-13C2-1,3,5-15N3

M. Briki et al., J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2024, 1236, 124039. (read article)

J. Roosendaal et al., J. Pharm. Biomed. Anal., 2019, 164, 16-26. (read article)

[13C2,15N4]-Decitabine

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