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Stable isotope

Nucleosyn provides Custom Stable Isotope (2H, 13C, 15N) compounds to support projects dedicated to : Bioanalytics, Omics research, Molecular Imaging, and Biomarker discovery.

[13C6]-Paclitaxel

CAS #
33069-62-4
Packing size
5mg, 10mg, 25mg, bulk
Anticancer drugTherapeutic Drug Monitoring (TDM)SIL
-Paclitaxel Image 1

Paclitaxel is a chemotherapy medication used to treat various cancers, including ovarian cancer, esophageal cancer, breast cancer, non-small-cell lung cancer, solid tumors such as Kaposi’s sarcoma, cervical cancer pancreatic cancer, bladder cancer, prostate cancer, and skin cancers such as melanoma. Paclitaxel is given by intravenous injection.

Stable isotope labeled [13C6]-Paclitaxel is intended for use as an internal standard for the quantification of Paclitaxel and Ritonavir by LC or GC-mass spectrometry.

Aspect
Solid
Purity
Chemical purity 95%; Isotopic Enrichment 98%
Solubility
DMSO
Molecular weight
859.87
Molecular formula

C4113C6H51NO14

IUPAC
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-9-(((2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-12-((benzoyl-13C6)oxy)-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b(2aH)-diyl diacetate

J. E. Adaway, B. G. Keevil, J. Chromatogr. B, 2012, 883-884, 33-49. (read article)

S. Q. Zhang, G. H. Chen, J. Chromatogr. Sci., 2008, 46, 220. (read article)

L. D. Vainchtein et al., Biomed. Chromatogr., 2006, 20, 139. (read article)

M. Briki et al., J. Chromatogr. B, 2024, 124039. (read article)

M. A. C. Vermunt et al., Cancer Chemother. Pharmacol., 2022, 89, 785-793. (read article)

S. M. Christner et al., J. Pharm. Biomed. Anal., 2019, 172, 26-32. (read article)

J. B. Bulitta et al., Cancer Chemother. Pharmacol., 2009, 63, 1035-1048. (read article)

J. B. Bulitta et al., Cancer Chemother. Pharmacol., 2009, 63, 1049-1063. (read article)

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