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Stable isotope

Nucleosyn provides Custom Stable Isotope (2H, 13C, 15N) compounds to support projects dedicated to : Bioanalytics, Omics research, Molecular Imaging, and Biomarker discovery.

[13C6]-Paclitaxel

CAS #
379688-61-6
Packing size
5mg, 10mg, 25mg, bulk
Therapeutic Drug Monitoring (TDM)SILAnticancer drug
-Paclitaxel Image 1

Paclitaxel is a chemotherapy medication used to treat various cancers, including ovarian cancer, oesophageal cancer, breast cancer, non-small-cell lung cancer, solid tumours such as Kaposi’s sarcoma, cervical cancer, pancreatic cancer, bladder cancer, prostate cancer, and skin cancers such as melanoma. Paclitaxel is given by intravenous injection.

Stable isotope labeled [13C6]-Paclitaxel is intended for use as an internal standard for the quantification of Paclitaxel and Ritonavir by LC or GC-mass spectrometry.

Aspect
Solid
Purity
Chemical purity 95%; Isotopic Enrichment 98%
Solubility
DMSO
Molecular weight
859.87
Molecular formula

C4113C6H51NO14

IUPAC
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-9-(((2R,3S)-3-(benzamido-13C6)-2-hydroxy-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b(2aH)-diyl diacetate

WO2001094328 A1 (read article)

M. S. Alexander et al., J. Chromatogr. B, 2003, 785, 253-261. (read article)

S-Q. Zhang, G-H. Chen, Biomed. Chromatogr., 2009, 23, 510-515. (read article)

S-Q. Zhang, G-H. Chen, J. Chromatogr. Sci., 2008, 46, 3, 220-224. (read article)

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