Stable isotope

Nucleosyn provides Custom Stable Isotope (²H, ¹³C, ¹⁵N) compounds to support projects dedicated to : Bioanalytics, Omics research, Molecular Imaging, and Biomarker discovery.

[13CD3]-Sorafenib

CAS #

1210608-86-8

Packing size

5mg, 10mg, 25mg, bulk

Anticancer drug Therapeutic Drug Monitoring (TDM)

Sorafenib is a kinase inhibitor used to treat primary kidney cancer (renal cell carcinoma), advanced primary liver cancer (hepatocellular carcinoma), FLT3-ITD positive AML, and radioactive iodine resistant advanced thyroid cancer. Sorafenib can be taken by mouth.

Stable isotope labeled [¹³CD₃]-Sorafenib is intended for use as an internal standard for the quantification of Sorafenib by LC or GC-mass spectrometry.

Aspect

Solid

Purity

Chemical purity 95%; Isotopic Enrichment 98%

Solubility

DMSO, DMF, MeOH, EtOH

Molecular weight

468.84

Molecular formula

C₂₀¹³CH₁₃D₃ClF₃N₄O₃

IUPAC

4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-(methyl-13C-d3)picolinamide

J. E. Adaway, B. G. Keevil, J. Chromatogr. B, 2012, 883-884, 33-49. (read article)

[13CD3]-Sorafenib

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