Nucleosyn provides Custom Stable Isotope (2H, 13C, 15N) compounds to support projects dedicated to : Bioanalytics, Omics research, Molecular Imaging, and Biomarker discovery.
[13C2,15N2]-Nilotinib
Nilotinib is an anticancer drug used to treat Philadelphia chromosome (Ph+)-positive chronic myelogenous leukemia (CML). It induces serious side effects such as QT prolongation, sudden death, pancreatitis, and liver problems.
Stable isotope labeled [13C2,15N2]-Nilotinib is intended for use as an internal standard for the quantification of Nilotinib by LC or GC-mass spectrometry.
C2613C2H22F3N515N2O
J. E. Adaway, B. G. Keevil, J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2012, 883-884, 33-49. (read article)
R. A. Parise et al., J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2009, 877, 1894-1900. (read article)