Stable isotope

Nucleosyn provides Custom Stable Isotope (²H, ¹³C, ¹⁵N) compounds to support projects dedicated to : Bioanalytics, Omics research, Molecular Imaging, and Biomarker discovery.

[D6]-Lapatinib

CAS #

1210608-87-9

Packing size

5mg, 10mg, 25mg, bulk

Anticancer drug Therapeutic Drug Monitoring (TDM)

Lapatinib is used to treat women’s breast cancer in combination with other chemotherapeutic agents such as anthracycline, taxane-derived drugs, or trastuzumab.

Stable isotope labeled [D₆]-Lapatinib is intended for use as an internal standard for the quantification of Lapatinib by LC or GC-mass spectrometry.

Aspect

Solid

Purity

Chemical purity 95%; Isotopic Enrichment 98%

Solubility

DMSO

Molecular weight

587.10

Molecular formula

C₂₉H₂₀D₆ClFN₄O₄S

IUPAC

N-(3-chloro-4-((3-fluorophenyl-2,4,5,6-d4)methoxy-d2)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine

J. E. Adaway, B. G. Keevil, J. Chromatogr. B, 2012, 883-884, 33-49. (read article)

F. Bai et al., J. Chromatogr. B: Anal. Technol. Biomed. Life Sci., 2006, 831, 169. (read article)

[D6]-Lapatinib

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