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Stable isotope

Nucleosyn provides Custom Stable Isotope (2H, 13C, 15N) compounds to support projects dedicated to : Bioanalytics, Omics research, Molecular Imaging, and Biomarker discovery.

[D3]-Linezolid

CAS #
1127120-38-0
Packing size
5mg, 10mg, 25mg, bulk
Stable Isotope Labeled CompoundAntibioticTherapeutic Drug Monitoring (TDM)Bacterial infectionAnalytical Standards
-Linezolid Image 1

Linezolid is a synthetic antibiotic used against Gram-positive bacteria that are resistant to other antibiotics such as streptococci, vancomycin-resistant enterococci (VRE), or methicillin-resistant Staphylococcus aureus (MRSA). Although Linezolid is mostly used to treat skin infections and pneumonia, it may also treat other infections including drug-resistant tuberculosis. Linezolid can be taken by mouth or injected into a vein.

Stable isotope labeled [D3]-Linezolid is intended for use as an internal standard for the quantification of Linezolid by LC or GC-mass spectrometry.

Aspect
Powder
Purity
Chemical purity 95%; Isotopic Enrichment 98%
Solubility
Water
Molecular weight
340.37
Molecular formula

C16H17D3FN3O4

IUPAC
(S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide-2,2,2-d3

S. Van Vooren, A. G. Verstraete, Biomed. Chromatogr., 2021, 35, e5092. read article

N. El-Najjar et al., Drug Test Anal., 2018, 10, 584-591. read article

C. Mabilat et al., Eur. J. Clin. Microbiol. Infect. Dis., 2020, 39, 791-797. read article

C. Roger, J. A. Roberts, L. Muller, Clin. Pharmacokinet., 2018, 57, 559-575. read article

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