Stable isotope

Nucleosyn provides Custom Stable Isotope (²H, ¹³C, ¹⁵N) compounds to support projects dedicated to : Bioanalytics, Omics research, Molecular Imaging, and Biomarker discovery.

[D3]-Vinorelbine ditartrate salt

CAS #

N/A

Packing size

5mg, 10mg, 25mg, bulk

Anticancer drug Therapeutic Drug Monitoring (TDM)

Vinorelbine is a vinca-alkaloid used to treat several types of cancers including breast cancer, non-small cell lung cancer, and rhabdomyosarcoma. It induces serious side effects such as shortness of breath and bone marrow suppression.

Stable isotope labeled [D₃]-Vinorelbine ditartrate salt is intended for use as an internal standard for the quantification of Vinorelbine by LC or GC-mass spectrometry.

Aspect

White solid

Purity

Chemical purity 95%; Isotopic Enrichment 98%

Solubility

DMSO, MeOH

Molecular weight

1082.14

Molecular formula

C₅₃H₆₃D₃N₄O₂₀

IUPAC

methyl (3aR,3a1R,4R,5S,5aR,10bR)-4-acetoxy-3a-ethyl-9-((2R,6R,8S)-4-ethyl-8-((methoxy-d3)carbonyl)-1,3,6,7,8,9-hexahydro-2,6-methanoazecino[4,3-b]indol-8-yl)-5-hydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate bis-tartrate

M. Briki et al., J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2024, 1236, 124039. (read article)

G. Corona et al., Biomed. Chromatogr., 2018, e4282. (read article)

[D3]-Vinorelbine ditartrate salt

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