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Stable isotope

Nucleosyn provides Custom Stable Isotope (2H, 13C, 15N) compounds to support projects dedicated to : Bioanalytics, Omics research, Molecular Imaging, and Biomarker discovery.

[D4]-Cyclophosphamide

CAS #
173547-45-0
Packing size
5mg, 10mg, 25mg, bulk
Anticancer drugTherapeutic Drug Monitoring (TDM)SIL
-Cyclophosphamide Image 1

Cyclophosphamide is an immunosuppressive drug used to treat various types of cancers and diseases, including lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer, small-cell lung cancer, neuroblastoma, and sarcoma. Due to its high toxicity, this alkylating agent should be replaced as soon as possible by less toxic drugs. Cyclophosphamide can be taken by mouth or injection into a vein.

Stable isotope labeled [D4]-Cyclophosphamide is intended for use as an internal standard for the quantification of Cyclophosphamide by LC or GC-mass spectrometry.

Aspect
White solid
Purity
Chemical purity 95%; Isotopic Enrichment 98%
Solubility
Chloroform (slightly), MeOH (slightly)
Molecular weight
265.11
Molecular formula

C7H11D4Cl2N2O2P

IUPAC
2-(bis(2-chloroethyl)amino)-1,3,2-oxazaphosphinane 2-oxide-4,4,5,5-d4

M. Briki et al., J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2024, 1236, 124039. (read article)

C. Ekhart et al., J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2007, 854, 1-2, 345-349. (read article)

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