Stable isotope

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[D4]-N-acetyl sulfamethoxazole

CAS #

1215530-54-3

Packing size

5mg, 10mg, 25mg, bulk

Stable Isotope Labeled Compound Metabolite

N-acetyl sulfamethoxazole is the main metabolite of sulfamethoxazole. It has no antibacterial activity but can cause nephrotoxicity (crystalluria and haematuria) when its concentration is above 75 mg/L.

Stable isotope labeled [D₄]-N-acetyl sulfamethoxazole is intended for use as an internal standard for the quantification of N-acetyl sulfamethoxazole by LC or GC-mass spectrometry.

Aspect

Powder

Purity

Chemical purity 95%; Isotopic Enrichment 98%

Solubility

Water

Molecular weight

299.34

Molecular formula

C₁₂H₉D₄N₃O₄S

IUPAC

N-(4-(N-(5-methylisoxazol-3-yl)sulfamoyl)phenyl-2,3,5,6-d4)acetamide

X. M. Mekking et al., J. Antimicrob. Chemother, 2024, dkae047. read article

D. M. Burger, N. G. L. Jager, Sulfonamides, dihydrofolate reductase inhibitors and dapsone. In: Aranda JV, van den Anker JN, eds. Yaffe and Aranda’s Neonatal and Pediatric Pharmacology: Therapeutic Principles in Practice. 5th edn. Wolters Kluwer Health, 2021, 340–346. read article

[D4]-N-acetyl sulfamethoxazole

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