Stable isotope

Nucleosyn provides Custom Stable Isotope (²H, ¹³C, ¹⁵N) compounds to support projects dedicated to : Bioanalytics, Omics research, Molecular Imaging, and Biomarker discovery.

[D5]-Ceftazidime

Packing size

5mg, 10mg, 25mg, bulk

Analytical Standards Bacterial infection

Ceftazidime is a third-generation cephalosporin antibiotic used to treat numerous bacterial infections, including joint infections, meningitis, pneumonia, sepsis, urinary tract infections, malignant otitis externa, Pseudomonas aeruginosa infection, and vibrio infection. This β-lactam is given into a vein, muscle or eye.

Stable isotope labeled [D₅]-Ceftazidime is intended for use as an internal standard for the quantification of Ceftazidime by LC or GC-mass spectrometry.

Aspect

Powder

Purity

Chemical purity 95%; Isotopic Enrichment 98%

Solubility

Water

Molecular weight

551.60

Molecular formula

C₂₂H₁₇D₅N₆O₇S₂

IUPAC

(6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(((2-carboxypropan-2-yl)oxy)imino)acetamido)-8-oxo-3-((pyridin-1-ium-1-yl-d5)methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

S. Cairoli et al., Biomed. Chromatogr., 2020, 34, e4880. read article

S. Van Vooren, A. G. Verstraete, Biomed. Chromatogr., 2021, 35, e5092. read article

X. M. Mekking et al., J. Antimicrob. Chemother, 2024, dkae047. read article

N. El-Najjar et al., Drug Test Anal., 2018, 10, 584-591. read article

C. Mabilat et al., Eur. J. Clin. Microbiol. Infect. Dis., 2020, 39, 791-797. read article

[D5]-Ceftazidime

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