Stable isotope

Nucleosyn provides Custom Stable Isotope (²H, ¹³C, ¹⁵N) compounds to support projects dedicated to : Bioanalytics, Omics research, Molecular Imaging, and Biomarker discovery.

[D5]-Piperacillin

Packing size

5mg, 10mg, 25mg, bulk

Synonyme(s)

[D5]-Piperacil

Stable Isotope Labeled Compound Antibiotic

Piperacillin is a broad-spectrum antibiotic. This β-lactam is almost exclusively used in combination with the beta-lactamase inhibitor Tazobactam for the treatment of serious infections, including hospital-acquired pneumonia, and infections caused by anaerobic Gram-negative rods. Piperacillin is given by intravenous or intramuscular injection.

Stable isotope labeled [D₅]-Piperacillin is intended for use as an internal standard for the quantification of Piperacillin by LC or GC-mass spectrometry.

Aspect

Powder

Purity

Chemical purity 95%; Isotopic Enrichment 98%

Solubility

Water

Molecular weight

522.59

Molecular formula

C₂₃H₂₂D₅N₅O₇S

IUPAC

(2S,5R,6R)-6-((R)-2-(4-(ethyl-d5)-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

S. Van Vooren, A. G. Verstraete, Biomed. Chromatogr., 2021, 35, e5092. read article

X. M. Mekking et al., J. Antimicrob. Chemother, 2024, dkae047. read article

N. El-Najjar et al., Drug Test Anal., 2018, 10, 584-591. read article

C. Mabilat et al., Eur. J. Clin. Microbiol. Infect. Dis., 2020, 39, 791-797. read article

[D5]-Piperacillin

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