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Stable isotope

Nucleosyn provides Custom Stable Isotope (2H, 13C, 15N) compounds to support projects dedicated to : Bioanalytics, Omics research, Molecular Imaging, and Biomarker discovery.

[D5]-Piperacillin

Packing size
5mg, 10mg, 25mg, bulk
Synonyme(s)
[D5]-Piperacil
Stable Isotope Labelled CompoundBacterial infectionBeta-lactamAntibioticStable Isotope Labeled CompoundTherapeutic Drug Monitoring (TDM)Analytical Standards
-Piperacillin Image 1

Piperacillin is a broad-spectrum antibiotic. This β-lactam is almost exclusively used in combination with the beta-lactamase inhibitor Tazobactam for the treatment of serious infections, including hospital-acquired pneumonia, and infections caused by anaerobic Gram-negative rods. Piperacillin is given by intravenous or intramuscular injection.

Stable isotope labeled [D5]-Piperacillin is intended for use as an internal standard for the quantification of Piperacillin by LC or GC-mass spectrometry.

Aspect
Powder
Purity
Chemical purity 95%; Isotopic Enrichment 98%
Solubility
Water
Molecular weight
522.59
Molecular formula

C23H22D5N5O7S

IUPAC
(2S,5R,6R)-6-((R)-2-(4-(ethyl-d5)-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

S. Van Vooren, A. G. Verstraete, Biomed. Chromatogr., 2021, 35, e5092. read article

X. M. Mekking et al., J. Antimicrob. Chemother, 2024, dkae047. read article

N. El-Najjar et al., Drug Test Anal., 2018, 10, 584-591. read article

C. Mabilat et al., Eur. J. Clin. Microbiol. Infect. Dis., 2020, 39, 791-797. read article

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