Stable isotope

Nucleosyn provides Custom Stable Isotope (²H, ¹³C, ¹⁵N) compounds to support projects dedicated to : Bioanalytics, Omics research, Molecular Imaging, and Biomarker discovery.

[D5]-Tamoxifen

CAS #

157698-32-3

Packing size

5mg, 10mg, 25mg, bulk

Anticancer drug Therapeutic Drug Monitoring (TDM)

Tamoxifen is a selective estrogen receptor modulator used to prevent breast cancer for both women and men. Studies are currently ongoing to treat other types of cancer with Tamoxifen. Other applications are the treatment of infertility, gynecomastia, and early puberty. Tamoxifen can be taken by mouth as a tablet or solution.

Stable isotope labeled [D₅]-Tamoxifen is intended for use as an internal standard for the quantification of Tamoxifen by LC or GC-mass spectrometry.

Aspect

Solid

Purity

Chemical purity 95%; Isotopic Enrichment 98%

Solubility

DMSO, DMF, EtOH

Molecular weight

376.55

Molecular formula

C₂₆H₂₄D₅NO

IUPAC

(Z)-2-(4-(1,2-diphenylbut-1-en-1-yl-3,3,4,4,4-d5)phenoxy)-N,N-dimethylethan-1-amine

J. E. Adaway, B. G. Keevil, J. Chromatogr. B, 2012, 883-884, 33-49. (read article)

S. F. Teunissen et al., J. Chromatogr. B: Anal. Technol. Biomed. Life Sci., 2009, 877, 2519. (read article)

J. Gjerde et al., J. Chromatogr. A, 2005, 1082, 6. (read article)

S. F. Teunissen et al., J. Chromatogr. B: Anal. Technol. Biomed. Life Sci., 2011, 879, 1677. (read article)

[D5]-Tamoxifen

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