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Stable isotope

Stable isotope

Nucleosyn provides Custom Stable Isotope (2H, 13C, 15N) compounds to support projects dedicated to : Bioanalytics, Omics research, Molecular Imaging, and Biomarker discovery.

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  • [13C5]-Azacytidine

    -Azacytidine Image 1
    Stable isotope

    Azacytidine is a chemical analog of cytidine which is used to treat myelodysplastic syndrome (MDS), myeloid leukemia, ...

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    Anticancer drugTherapeutic Drug Monitoring (TDM)SIL
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  • [D11]-Capecitabine

    -Capecitabine Image 1
    Stable isotope

    Capecitabine is an anticancer drug used to treat breast cancer (advanced or metastatic), gastric cancer (unresectable ...

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    Anticancer drugTherapeutic Drug Monitoring (TDM)SIL
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  • [13C,15N2]-5’-Deoxy-5-fluorocytidine

    -5’-Deoxy-5-fluorocytidine Image 1
    Stable isotope

    5’-Deoxy-5-fluorocytidine is an intermediate metabolite of Capecitabine. Capecitabine is converted by carboxylestera...

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    Anticancer drugTherapeutic Drug Monitoring (TDM)SIL
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  • [13C,15N2]-5-Fluorouracil

    -5-Fluorouracil Image 1
    Stable isotope

    5-Fluorouracil (5-FU) is a metabolite of Capecitabine. Capecitabine is converted by carboxylesterase to 5'-Deoxy-5-flu...

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    Anticancer drugTherapeutic Drug Monitoring (TDM)SIL
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  • [13C,15N2]-5’-Deoxy-5-fluorouridine

    -5’-Deoxy-5-fluorouridine Image 1
    Stable isotope

    5’-Deoxy-5-fluorouridine, also known as Doxifluridine, is a second-generation nucleoside analog prodrug used as a cy...

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    Anticancer drugTherapeutic Drug Monitoring (TDM)SIL
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  • [13C,15N2]-5-Fluorodihydrouracil

    -5-Fluorodihydrouracil Image 1
    Stable isotope

    5-Fluorodihydrouracil is an active metabolite of the thymidylate synthase inhibitor prodrug 5-Fluorouracil. It is form...

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    Anticancer drugTherapeutic Drug Monitoring (TDM)SIL
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  • [15N2]-5-Fluorouracil

    -5-Fluorouracil Image 1
    Stable isotope

    5-Fluorouracil (5-FU) is a metabolite of Capecitabine. Capecitabine is converted by carboxylesterase to 5'-Deoxy-5-flu...

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    Anticancer drugTherapeutic Drug Monitoring (TDM)SIL
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  • [13C3]-N-Carbamoyl-2-fluoro-β-alanine

    -N-Carbamoyl-2-fluoro-β-alanine Image 1
    Stable isotope

    N-Carbamoyl-2-fluoro-β-alanine is a metabolite of Capecitabine.

    Stable isotope l...

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    Anticancer drugTherapeutic Drug Monitoring (TDM)SIL
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  • [13C,15N2]-Cytarabine

    -Cytarabine Image 1
    Stable isotope

    Cytarabine is a nucleoside analog and antimetabolite used in the treatment of several types of cancers including acute...

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    Anticancer drugTherapeutic Drug Monitoring (TDM)SIL
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  • [15N3]-Deoxycytidine

    -Deoxycytidine Image 1
    Stable isotope

    2’-Deoxycytidine is a deoxyribonucleoside that can be used as a precursor for the synthesis of active biomolecules. ...

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    Anticancer drugTherapeutic Drug Monitoring (TDM)SIL
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