Synthetic lipids

NucleoSyn produces and supplies synthetic lipids from milligrams to multi-kilos quantities.

18:0 DAP

CAS #

121315-93-3

Packing size

100 mg, 500 mg, 1 g, bulk (gram scale)

Synonyme(s)

DSDAP

Nanoparticle LNP

18:0 DAP is a cationic lipid and serves as a pH-sensitive transfection reagent. LNP derived from 18:0 DAP were used to delivered mRNA in order to treat monogenic retinal degenerative disorders. It might also be used in the preparation of “bubble liposomes” (BLs).

Aspect

Powder

Purity

98%

Solubility

CHCl3

Molecular weight

652,10

Molecular formula

C₄₁H₈₁NO₄

IUPAC

3-(dimethylamino)propane-1,2-diyl distearate

S. Patel et al., J. Control Release, 2019, 303, 91-100. read article

Y. Endo-Takahashi et al., Biomaterials, 2013, 34, 2807-2813. read article

18:0 DAP

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