
Synthetic lipids
NucleoSyn produces and supplies synthetic lipids from milligrams to multi-kilos quantities.
18:0 DAP
CAS #
121315-93-3
Packing size
100 mg, 500 mg, 1 g, bulk (gram scale)
Synonyme(s)
DSDAP

18:0 DAP is a cationic lipid and serves as a pH-sensitive transfection reagent. LNP derived from 18:0 DAP were used to delivered mRNA in order to treat monogenic retinal degenerative disorders. It might also be used in the preparation of “bubble liposomes” (BLs).
Aspect
Powder
Purity
98%
Solubility
CHCl3
Molecular weight
652,10
Molecular formula
C41H81NO4
IUPAC
3-(dimethylamino)propane-1,2-diyl distearate
S. Patel et al., J. Control Release, 2019, 303, 91-100. read article
Y. Endo-Takahashi et al., Biomaterials, 2013, 34, 2807-2813. read article