Synthetic lipids

NucleoSyn produces and supplies synthetic lipids from milligrams to multi-kilos quantities.

DC-Chol HCl

CAS #

137056-72-5

Packing size

100 mg, 500 mg, 1 g, bulk (gram scale)

LNP Nanoparticle

DC-cholesterol can be combined with DOPE (850725) to form cationic liposomes that can be used as intracellular delivery nanocarrier for nucleic acids.

Aspect

Powder

Purity

98%

Solubility

DMSO, MeOH

Molecular weight

537,27

Molecular formula

C₃₂H₅₇ClN₂O₂

IUPAC

2-(((((3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)carbonyl)amino)-N,N-dimethylethan-1-aminium chloride

G. Lou et al., J. Control Release, 2020, 325, 370-379. read article

K. Yang et al., Acta. Biomater., 2020, 106, 314-327. read article

T. Michel et al., Mol. Ther. Nucleic Acids, 2017, 8, 459-468. read article

R. Zhang et al., J. Biomater. Appl., 2015, 30 (3), 351-360. read article

Y. Men et al., Int. J. Nanomedicine, 2011, 6, 3125-3137. read article

DC-Chol HCl

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