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Synthetic lipids

NucleoSyn produces and supplies synthetic lipids from milligrams to multi-kilos quantities.

DOBAQ

CAS #
1360461-69-3
Packing size
100 mg, 500 mg, 1 g, bulk (gram scale)
AmmoniumNanoparticleLNPLiposomeTransfectionCationic lipid
DOBAQ Image 1

DOBAQ is a pH-sensitive lipid, which is cationic at pH= 4.0 It forms small, monodisperse liposomes with over 80% siRNA encapsulation.

Aspect
Powder
Purity
98%
Solubility
CHCl3
Molecular weight
782,20
Molecular formula

C49H83NO6

IUPAC
4-(((2,3-bis(oleoyloxy)propyl)dimethylammonio)methyl)benzoate

C. L. Walsh, J. Nguyen, F. C. Szoka, Chem Commun, 2012, 48, 45, 5575-5577. read article

O. Staufer et al., Biomaterials, 2021, 264, 120203. read article

S. Draffehn, M. U. Kumke, Mol. Pharmaceutics, 2016, 13, 1608-1617. read article

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