Synthetic lipids

NucleoSyn produces and supplies synthetic lipids from milligrams to multi-kilos quantities.

DOBAQ

CAS #

1360461-69-3

Packing size

100 mg, 500 mg, 1 g, bulk (gram scale)

DOBAQ is a pH-sensitive lipid, which is cationic at pH= 4.0 It forms small, monodisperse liposomes with over 80% siRNA encapsulation.

Aspect

Powder

Purity

98%

Solubility

CHCl3

Molecular weight

782,20

Molecular formula

C₄₉H₈₃NO₆

IUPAC

4-(((2,3-bis(oleoyloxy)propyl)dimethylammonio)methyl)benzoate

C. L. Walsh, J. Nguyen, F. C. Szoka, Chem Commun, 2012, 48, 45, 5575-5577. read article

O. Staufer et al., Biomaterials, 2021, 264, 120203. read article

S. Draffehn, M. U. Kumke, Mol. Pharmaceutics, 2016, 13, 1608-1617. read article

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