Synthetic lipids

NucleoSyn produces and supplies synthetic lipids from milligrams to multi-kilos quantities.

DOPE

CAS #

4004-05-1

Packing size

100 mg, 500 mg, 1 g, bulk (gram scale)

Phospholipid Ammonium

DOPE is a neutral phospholipid and displays sensitivity towards pH change and has been used in the preparation of liposome and giant unilamellar vesicles (GUVs). DOPE can be used as an emulsifier to facilitate DNA-liposome complex transport across membranes.

Aspect

Solid

Purity

98%

Solubility

EtOH, DMSO

Molecular weight

744,05

Molecular formula

C₄₁H₇₈NO₈P

IUPAC

2-ammonioethyl ((R)-2,3-bis(oleoyloxy)propyl) phosphate

R. C. MacDonald, V. A. Rakhmanova, K. L. Choi, H. S. Rosenzweig, M. K. Lahiri, J. Pharm. Sci., 1999, 88, 9, 896-904. read article

S. K. Misra, J. Biswas, P. Kondaiah, S. Bhattacharya, Plos One, 2013, 8, 7, e68305. read article

Y. Chen, J. Sun, Y. Lu, C. Tao, J. Huang, H. Zhang, Y. Yu, H. Zou, J. Gao, Y. Zhong, Int. J. Nanomedicine, 2013, 8, 1573-1593. read article

DOPE

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