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Synthetic lipids

NucleoSyn produces and supplies synthetic lipids from milligrams to multi-kilos quantities.

DOPE

CAS #
4004-05-1
Packing size
100 mg, 500 mg, 1 g, bulk (gram scale)
PhospholipidAmmoniumNanoparticleLiposomeTransfectionCationic lipidLipid
DOPE Image 1

DOPE is a neutral phospholipid and displays sensitivity towards pH change and has been used in the preparation of liposome and giant unilamellar vesicles (GUVs). DOPE can be used as an emulsifier to facilitate DNA-liposome complex transport across membranes.

Aspect
Solid
Purity
98%
Solubility
EtOH, DMSO
Molecular weight
744,05
Molecular formula

C41H78NO8P

IUPAC
2-ammonioethyl ((R)-2,3-bis(oleoyloxy)propyl) phosphate

R. C. MacDonald, V. A. Rakhmanova, K. L. Choi, H. S. Rosenzweig, M. K. Lahiri, J. Pharm. Sci., 1999, 88, 9, 896-904. read article

S. K. Misra, J. Biswas, P. Kondaiah, S. Bhattacharya, Plos One, 2013, 8, 7, e68305. read article

Y. Chen, J. Sun, Y. Lu, C. Tao, J. Huang, H. Zhang, Y. Yu, H. Zou, J. Gao, Y. Zhong, Int. J. Nanomedicine, 2013, 8, 1573-1593. read article

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