Synthetic lipids

NucleoSyn produces and supplies synthetic lipids from milligrams to multi-kilos quantities.

Lipid 29

CAS #

2244716-55-8

Packing size

100 mg, 500 mg, 1 g, bulk (gram scale)

mRNA delivery Nanoparticle

Lipid 29 is an ionizable amino lipid (pKa = 6.91). Lipid 29 is used in combination with other lipids for the formulation of lipid nanoparticules (LNPs) for mRNA delivery. It has been shown that Lipid 29 improves the performances of the corresponding lipid nanoparticle through specific interactions with mRNA.

Aspect

White waxy solid

Purity

98%

Solubility

EtOH

Molecular weight

860,36

Molecular formula

C₅₂H₉₇N₃O₆

IUPAC

heptadecan-9-yl 8-((3-((2-(methylamino)-3,4-dioxocyclobut-1-en-1-yl)amino)propyl)(8-oxo-8-(undecan-3-yloxy)octyl)amino)octanoate

M. Cornebise, et al., Adv. Funct. Mater., 2022, 32, 2106727. read article

Lipid 29

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