Synthetic lipids

NucleoSyn produces and supplies synthetic lipids from milligrams to multi-kilos quantities.

LP-01

CAS #

1799316-64-5

Packing size

100 mg, 500 mg, 1 g, bulk (gram scale)

Synonyme(s)

CIN-16645

mRNA delivery siRNA delivery

LP-01 is a novel biodegradable (via labile ester linkages) and ionizable lipid that has been used in combination with other lipids to encapsulate and deliver siRNA, mRNA, sgRNA, DNA, and small molecules into cells and tissues.

Aspect

Clear oil

Purity

98%

Solubility

EtOH, DMSO, DMF, DCM, MeCN

Molecular weight

852.29

Molecular formula

C₅₀H₉₃NO₉

IUPAC

3-((4,4-bis(octyloxy)butanoyl)oxy)-2-((((3-(diethylamino)propoxy)carbonyl)oxy)methyl)propyl (9Z,12Z)-octadeca-9,12-dienoate

J. D. Finn, et al., Cell Rep., 2018, 22, 2227-2235. read article

K. Lam, et al., Adv. Mater., 2023, 35, 2209624. read article

LP-01

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