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Stable isotope

Nucleosyn provides Custom Stable Isotope (2H, 13C, 15N) compounds to support projects dedicated to : Bioanalytics, Omics research, Molecular Imaging, and Biomarker discovery.

[D5]-Phosphatidylethanol / [d5] - PEth ammonium salt

CAS #
1612140-92-7
Packing size
1, 5, 10, 25, 50mg, custom packing size on request
Synonyme(s)
[D5]-PEth 16:0/18:1
Stable Isotope Labelled CompoundBiomarkerStable Isotope Labeled CompoundTherapeutic Drug Monitoring (TDM)Analytical StandardsDiagnostic tool & biomarker
-Phosphatidylethanol / - PEth ammonium salt Image 1

Stable isotope labeled PEth is intended for use as an internal standard for the quantification of PEth by LC or GC-mass spectrometry. Phosphatidyl ethanol (PEth) is an abnormal phospholipid formed in the erythrocyte membrane exclusively in the presence of ethanol. It is described as exhibiting a high diagnostic sensitivity and specificity for detecting active chronic excessive drinking behaviors. It may also be useful for characterizing the drinking pattern (i.e. identifying binge drinking episodes) and differentiating light-moderate drinking from abstinence. Alcohol biomarkers are physiological indicators of alcohol exposure or ingestion and may reflect the presence of an alcohol use disorder” Substance Abuse Treatment Advisory. Sept 2006, Vol 5, Issue 4.

Purity
Chemical purity 95%; Isotopic Enrichment 98%
Solubility
chlorofom (CHCl3) /methanol (MeOH)
Molecular weight
725,06
Molecular formula

C39H73D5NO8P

IUPAC
ammonium (R)-ethyl-d5 (2-(oleoyloxy)-3-(palmitoyloxy)propyl) phosphate

N. Kummer et al., Anal. Bioanal. Chem., 2016, 408, 3, 825-838. read article

A. K. Brown et al., AIDS Behav., 2017, 21, 1938-1949. read article

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