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Nucleosyn offers an extensive line of standard phosphoramidites, RNA phosphoramidites, specialty amidites and modifiers, solid supports CPG, reagents and solvents for a wide variety of instruments.

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DNA-RNA   Synthetic lipids   Stable isotope   Custom synthesis
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  • DC-Chol

    DC-Chol Image 1
    Synthetic lipids

    DC-cholesterol can be combined with DOPE (850725) to form cationic liposomes that can be used as intracellular delivery nanocarrier for nucleic aci...

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    LNP Nanoparticule
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  • OH-Chol

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    Synthetic lipids

    OH-Chol is a cationic cholesterol derivative. It has been used in cationic nanoparticles in combination with Tween 80 to transfect pDNA and siRNA i...

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    LNP Transfection Nanoparticule siRNA delivery
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  • 5'-ODMT-Bz-difluoro-deoxycytidine

    5'-ODMT-Bz-difluoro-deoxycytidine Image 1
    DNA-RNA

    dFdC phosphoramidite, also known as Gemcitabine 3'-CE phosphoramidite, is a nucleoside phosphoramidite used in oligonucleotide synthesis. A chemica...

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    Phosphoramidite DNA & RNA Supports DNA & RNA Nucleosides DNA & RNA Analogs
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  • DOPE

    DOPE Image 1
    Synthetic lipids

    DOPE is a neutral phospholipid and displays sensitivity towards pH change and has been used in the preparation of liposome and giant unilamellar ve...

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    Phospholipid Ammonium Nanoparticule Liposome Transfection Cationic lipid Lipid
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  • ALC-0159

    ALC-0159 Image 1
    Synthetic lipids

    ALC-0159 is a lipid excipient. It has been deployed in the Pfizer-BioNTech SARS-CoV-2 mRNA vaccine in addition to ALC-0315, DSPC, and cholesterol.<...

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    Excipient Pegylated Ammonium Nanoparticule LNP Liposome Transfection Cationic lipid
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  • DOBAQ

    DOBAQ Image 1
    Synthetic lipids

    DOBAQ is a pH-sensitive lipid, which is cationic at pH= 4.0 It forms small, monodisperse liposomes with over 80% siRNA encapsulation.

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    Ammonium Cationic lipid Transfection Liposome LNP Nanoparticule
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  • DSPC

    DSPC Image 1
    Synthetic lipids

    DSPC has a relatively high main phase transition temperature (55.6 °C). It is commonly used in the generation of micelles, liposomes, artificial m...

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    Phospholipid Ammonium Nanoparticule LNP Liposome Transfection Cationic lipid
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  • 306Oi10

    306Oi10 Image 1
    Synthetic lipids

    306Oi10 is a biodegradable, branched chain lipidoid. 306Oi10 has been used to co-deliver three mRNAs (firefly luciferase, mCherry, and erythro...

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    Nanoparticule LNP Liposome Transfection Cationic lipid mRNA delivery
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  • ALC-0315

    ALC-0315 Image 1
    Synthetic lipids

    ALC-0315 is one of the components in the BNT162b2 (Pfizer-Biontech) vaccine against SARS-CoV-2. Administration of (SARS-CoV-2) mRNA in LNPs constru...

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    Nanoparticule LNP Liposome Transfection Cationic lipid mRNA delivery
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  • ATX-001

    ATX-001 Image 1
    Synthetic lipids

    ATX-001 and ATX-002 are lipids constructed from an SAR study to optimize physicochemical parameters resulting in good in vivo activity within a ran...

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    Cationic lipid Transfection Liposome LNP Nanoparticule
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