Catalog
Nucleosyn offers an extensive line of standard phosphoramidites, RNA phosphoramidites, specialty amidites and modifiers, solid supports CPG, reagents and solvents for a wide variety of instruments.
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DC-Chol
DC-cholesterol can be combined with DOPE (850725) to form cationic liposomes that can be used as intracellular delivery nanocarrier for nucleic aci...
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OH-Chol
OH-Chol is a cationic cholesterol derivative. It has been used in cationic nanoparticles in combination with Tween 80 to transfect pDNA and siRNA i...
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5'-ODMT-Bz-difluoro-deoxycytidine
dFdC phosphoramidite, also known as Gemcitabine 3'-CE phosphoramidite, is a nucleoside phosphoramidite used in oligonucleotide synthesis. A chemica...
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DOPE
DOPE is a neutral phospholipid and displays sensitivity towards pH change and has been used in the preparation of liposome and giant unilamellar ve...
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ALC-0159
ALC-0159 is a lipid excipient. It has been deployed in the Pfizer-BioNTech SARS-CoV-2 mRNA vaccine in addition to ALC-0315, DSPC, and cholesterol.<...
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DOBAQ
DOBAQ is a pH-sensitive lipid, which is cationic at pH= 4.0 It forms small, monodisperse liposomes with over 80% siRNA encapsulation.
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DSPC
DSPC has a relatively high main phase transition temperature (55.6 °C). It is commonly used in the generation of micelles, liposomes, artificial m...
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306Oi10
306Oi10 is a biodegradable, branched chain lipidoid. 306Oi10 has been used to co-deliver three mRNAs (firefly luciferase, mCherry, and erythro...
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ALC-0315
ALC-0315 is one of the components in the BNT162b2 (Pfizer-Biontech) vaccine against SARS-CoV-2. Administration of (SARS-CoV-2) mRNA in LNPs constru...
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ATX-001
ATX-001 and ATX-002 are lipids constructed from an SAR study to optimize physicochemical parameters resulting in good in vivo activity within a ran...