Stable isotope

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[13C6]-Tobramycin

CAS #

N/A

Packing size

1, 5, 10, 25, 50mg, custom packing size on request

Synonyme(s)

4-amino-2-(((1S,2R,3R,4S,6R)-4,6-diamino-3-(((2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxytetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-6-(hydroxy-l2-methyl-13C)-2H-2l3,3l3,4l3,5l3,6l3-pyran-3,5(4H,6H)-diol-2,3,4,5,6-13C5

Stable Isotope Labelled Compound Stable Isotope Labeled Compound

Tobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius that is used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas.

Stable isotope labeled Tobramycin is intended for use as an internal standard for the quantification of Tobramycin by LC or GC-mass spectrometry, an alternative to immunoassay based quantification.

Purity

Chemical purity 95%; Isotopic Enrichment 98%

Solubility

Water (H2O, 50mg/mL), Dimethylsulfoxide (DMSO)

Molecular weight

466,42

Molecular formula

C₁₂¹³C₆H₃₀N₅O₉

IUPAC

(2S,3R,4S,5S,6R)-4-amino-2-(((1S,2S,3R,4S,6R)-4,6-diamino-3-(((2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxytetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-6-(hydroxymethyl-13C)tetrahydro-2H-pyran-3,5-diol-2,3,4,5,6-13C5

Tobramycin Level Monitoring – Discrepancy between immunoassays. C.E. Shalapay et al. Clinical Chemistry, 2015, 61, 10, S214 – Abstract B-301 from AACC (American Association for Clinical Chemistry) 2015 annual meeting. read article

[13C6]-Tobramycin

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