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5'-Amino-Modifier C5-TFA

CAS #

139747-14-1

Packing size

250mg

Synonyme(s)

C5-TFA

DNA & RNA Supports DNA & RNA Nucleosides

C5-TFA Phosphoramidite was designed to functionalize the 5'-terminus of the target oligonucleotide and to introduce a primary amino group into an oligo. After TFA deprotection, the amino group could be immediately conjugated with activated carboxy group, and synthesis a stable amide linkage.

Aspect

Colorless oil

Purity

>95% (LC)

Solubility

MeCN

Molecular weight

399.39

Molecular formula

C₁₆H₂₉F₃N₃O₃P

IUPAC

2-cyanoethyl (5-(2,2,2-trifluoroacetamido)pentyl) diisopropylphosphoramidite

K. B. Grant, P. B. Dervan, Biochemistry, 1996, 35, 38, 12313–12319. read article

5'-Amino-Modifier C5-TFA

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