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DNA-RNA

Nuleosyn offers an extensive line of standard phosphoramidites, RNA phosphoramidites, specialty amidites and modifiers, solid supports CPG, reagents and solvents for a wide variety of instruments

5-Methyl-2’-deoxyCytidine

CAS #
105931-57-5
Packing size
100µmol, 250mg
Synonyme(s)
5-Methyl dC phosphoramidite
DNA & RNA SupportsDNA & RNA NucleosidesPhosphoramiditeDNA & RNA Analogs
5-Methyl-2’-deoxyCytidine Image 1

5-Methyl-2’-deoxyCytidine is used in the synthesis of 2’-deoxy-5-methylcytidine-containing oligonucleotides as antisense drugs.

Aspect
White solid
Purity
>95% (LC)
Solubility
MeCN
Molecular weight
847.95
Molecular formula

C47H54N5O8P

IUPAC
(2R,3S,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

J. K. Christman, G. Sheiknejad, C. J. Marasco, J. R. Sufrin, Proc. Natl. Acad. Sci. USA, 1995, 92, 7347 - 7351. read article

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