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5'-Thiol-Modifier-C6

CAS #

116919-17-6

Packing size

100µmol, 250mg

DNA & RNA Supports DNA & RNA Nucleosides

The 5’-Thiol-Modifier C6 is used to produce a thiol group at the 5’-terminus of a synthetic oligonucleotide. The thiol group can be used to attach a variety of products to the oligonucleotide, including fluorescent tags, biotin, and alkaline phosphatase.

Aspect

Colorless oil

Purity

>95% (LC)

Solubility

MeCN

Molecular weight

576.78

Molecular formula

C₃₄H₄₅N₂O₂PS

IUPAC

2-cyanoethyl (6-(tritylthio)hexyl) diisopropylphosphoramidite

C. Gnaccarini, S. Peter, U. Scheffer, S. Vonhoff, S. Klussmann, M. W. Göbel, J. Am. Chem. Soc., 2006, 128, 24, 8063–8067. read article

F. Seela, P. Ding, S. Budow, Bioconjugate Chem., 2011, 22, 4, 794–807. read article

F. Maurel, F. Debart, F. Cavelier, A. R. Thierry, B. Lebleu, J-J. Vasseur, E. Vivès, Bioorg. Med. Chem. Lett., 2005, 15, 22, 5084-5087. read article

5'-Thiol-Modifier-C6

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