Stable Isotope

Nucleosyn provides Custom Stable Isoptope (2H, 13C, 15N) Compounds to support projects dedicated to Bioanalytics, Omics research, Molecular Imaging and Biomarker discovery. Stable Isotope Labeled Compounds are commonly used as:

• Tracers in metabolism and Omic studies using mass spectrometry or NMR spectroscopy.
• Internal standards in quantitative bioanalysis by LC / MS.
• Tools to enhance PK of drugs, drug candidates (Deuterium medicinal chemistry).
• Tracers for assessing absolute bioavailability of drug candidate.
• And more…

For many years, Nucleosyn has built its experience in labeling a wide range of chemotypes such as heterocycles, natural products, amino acids & peptides… Our expertise allows us to perform incorporation of isotopic labels (2H, 15N or 13C or a combination of them), at specific positions of the compound, including site selective and multiple site selective schemes.