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5'- & 3'-Thiol-Modifiers

5'- & 3'-Thiol-Modifiers

5’-Thiol modifiers are phosphoramidites used to produce a functional thiol group on the 5’-terminus of targeted oligonucleotides. Thiol modification allows the attachment of a variety of products, such as fluorescent dyes, labeling with thiol-specific tags like maleimide and iodoacetamide compounds, biotin, and proteins. 3’-thiol-modifiers are used to produce 3’-thiol-modified oligonucleotides where a different label is desired for the 5’-terminus.

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5'-Amino & Internal Modifiers 5'- & 3'-Thiol-Modifiers 5'- & 3'-Phosphorylating-Modifiers Biotin Labeling Fluorescein Amidites Spacer Modifiers Duplex Modifiers Dark Quenchers 3'-Glyceryl-CPG 3'-Solid Support CPG
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  • 5'-Thiol-Modifier-C6

    5'-Thiol-Modifier-C6 Image 1
    DNA-RNA

    The 5’-Thiol-Modifier C6 is used to produce a thiol group at the 5’-terminus of a synthetic oligonucleotide. The t...

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    DNA & RNA SupportsDNA & RNA NucleosidesDNA & RNA AnalogsPhosphoramidite
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  • 3'-Thiol-Modifier-C3-SS-CPG1000

    3'-Thiol-Modifier-C3-SS-CPG1000 Image 1
    DNA-RNA

    The 3’-Thiol-Modifier-SS-C3-CPG is used to introduce 3’-thiol linkages with three atom spacers into oligonucleotid...

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    CPGPhosphoramiditeDNA & RNA SupportsDNA & RNA NucleosidesDNA & RNA Analogs
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  • 5'-Thiol-Modifier-C6-SS phosphoramidite

    5'-Thiol-Modifier-C6-SS phosphoramidite Image 1
    DNA-RNA

    The disulfide thiol modifiers may be used for introducing 5’-thiol linkages. This modification is used for oligo act...

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    PhosphoramiditeDNA & RNA SupportsDNA & RNA NucleosidesDNA & RNA Analogs
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