Dark Quenchers
Dark quenchers are commonly introduced at the 5’-terminal and 3’-terminal positions of oligonucleotides. DDQ1 type are quenching the lower wavelength dyes such as fluorescein. DDQ2 type have a broad absorbance spectrum centered around 650 nm.
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5'-Amino & Internal Modifiers 5'- & 3'-Thiol-Modifiers 5'- & 3'-Phosphorylating-Modifiers Biotin Labeling Fluorescein Amidites Spacer Modifiers Duplex Modifiers Dark Quenchers 3'-Glyceryl-CPG 3'-Solid Support CPG
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N-Quencher-2-CPG1000 (glycolate linker)
Commonly used quenchers encounter important limitations, such as a background increase with TAMRA due to its native fl...
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N-Quencher-1-CPG1000 (glycolate linker)
Commonly used quenchers encounter important limitations, such as a background increase with TAMRA due to its native fl...
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3'-Dabsyl-CPG1000
A molecular beacon probe1 has its natural fluorescence quenched in solution unless it is hybridized to the target sequ...
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dR-DDQ1 phosphoramidite
The Deep Dark Quencher 1 is a dark and non-fluorescent quencher, based on methyl red, and can be incorporated into oli...
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dR-DDQ1-CPG1000
The Deep Dark Quencher 1 is a dark and non-fluorescent quencher, based on methyl red, and can be incorporated into oli...
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dR-DDQ2 phosphoramidite
The Deep Dark Quencher 2 is a dark and non-fluorescent quencher, based on the diaminoanthraquinone Disperse Blue 3 and...
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dR-DDQ2-CPG1000
The Deep Dark Quencher 2 is a dark and non-fluorescent quencher, based on the diaminoanthraquinone Disperse Blue 3 and...
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Dabcyl-dT phosphoramidite
DABCYL is a dark quencher, commonly used for labelling oligos and peptides. The obtaiend conjugates are often used as ...
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3'-Dabcyl-CPG1000
DABCYL is a dark quencher, commonly used for labeling oligos and peptides. The obtained conjugates are often used as d...