Helper lipids
Helper lipids include phospholipids that can be subdivided into smaller categories like phosphatidic acids and phosphatidylethanolamine derivatives. Phosphatidic acids, including DOPA (4LSC4991 & 4LSC4992), have been used to generate various artificial membranes, such as micelles and liposomes. Phosphatidylethanolamine derivatives, including DOPE (4LSC3291) and DSPC (4LSC3288), are rather used as emulsifiers to assist DNA-liposome complex transport through membranes, or lipid nanoparticles (LNPs) stabilizers.
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Ionizable lipids Cationic lipids Helper lipids PEG lipids Cholesterol derivatives Isotope-labeled lipids Sphingolipids
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DOPC
DOPC is a helper lipid mostly used to prepare liposomes. In combination with DPPC, it generates bilayer LNPs for the d...
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rac-DOPA
DOPA may be used to create liposome templates to synthesize calcium phosphate nanoshells and in the formulation of lip...
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DOPA
DOPA may be used to create liposome templates to synthesize calcium phosphate nanoshells and in the formulation of lip...
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DOPE
DOPE is a neutral phospholipid and displays sensitivity towards pH change and has been used in the preparation of lipo...
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ALC-0159
ALC-0159 is a lipid excipient. It has been deployed in the Pfizer-BioNTech SARS-CoV-2 mRNA vaccine in addition to ALC-...
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DSPC
DSPC has a relatively high main phase transition temperature (55.6 °C). It is commonly used in the generation of mice...