Isotope-labeled lipids
For many years, Nucleosyn has built its experience in labeling a wide range of molecules. Our expertise allows us to perform the incorporation of isotopic labels at specific positions of the compound, including site-selective and multiple site-selective schemes. Nucleosyn provides custom-stable isotope lipids to support dedicated projects, such as therapeutic drug monitoring thanks to mass spectrometry.
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Ionizable lipids Cationic lipids Helper lipids PEG lipids Cholesterol derivatives Isotope-labeled lipids Sphingolipids
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[13C3]-Lipid 5
Lipid H (SM102) and Lipid 5 were used for the delivery of mRNA in primates and rapidly cleared from the body resulting...
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[D13]-DLin-MC3-DMA
DLin-MC3-DMA is a cationic lipid for siRNA mRNA, and vaccine delivery. Administration of DLin-MC3-DMA-based LNPs have ...
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[13C3]-DLin-MC3-DMA
DLin-MC3-DMA is a cationic lipid for siRNA mRNA, and vaccine delivery. Injection of DLi...
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[D9]-C16-Sphingomyelin (d18:1/16:0)
C16 Sphingomyelin is a naturally occurring sphingolipid. Dysregulated sphingolipid metabolism has become a common them...
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[13C6]-Glucosylsphingosine ([13C6]-GlSph)
Glucosylsphingosine (GlcSph) is a key biomarker of Gaucher Disease (GD). Glucosylsphingosine is a cytotoxic compound. ...
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[D5]-Phosphatidylethanol / [d5] - PEth ammonium salt
Stable isotope labeled PEth is intended for use as an internal standard for the quantification of PEth by LC or GC-mas...