Cationic lipids
Cationic lipids bear a positive permanently charged polar head, mostly as a quaternary ammonium salt. Cationic lipids can be used for mRNA delivery in multiple cell types thanks to their charged polar head which facilitates the encapsulation process (LNPs), neutralizes negative charges, and thus facilitates cell uptake.
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Ionizable lipids Cationic lipids Helper lipids PEG lipids Cholesterol derivatives Isotope-labeled lipids Sphingolipids
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DOBAQ
DOBAQ is a pH-sensitive lipid, which is cationic at pH= 4.0 It forms small, monodisperse liposomes with over 80% siRNA...
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DDAB
DDAB is a non-toxic double-chained quaternary ammonium surfactant. It has been used for transfection in a guinea pig m...
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DOTAP
DOTMA and DOTAP are among the most widely used cationic lipids for gene transfection in vitro and in vivo. DOTMA and D...
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DOTMA
DOTMA and DOTAP are among the most widely used cationic lipids for gene transfection in vitro and in vivo. DOTMA and D...