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Synthetic lipids

Synthetic lipids

NucleoSyn produces and supplies synthetic lipids from milligrams to multi-kilos quantities.

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DNA-RNA  Synthetic lipids  Stable isotope  Custom synthesis services
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Ionizable lipids
Cationic lipids
Helper lipids
PEG lipids
Cholesterol derivatives
Isotope-labeled lipids
Sphingolipids
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  • DC-Chol HCl

    DC-Chol HCl Image 1
    Synthetic lipids

    DC-cholesterol can be combined with DOPE (850725) to form cationic liposomes that can be used as intracellular deliver...

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    LNPNanoparticle
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  • OH-Chol

    OH-Chol Image 1
    Synthetic lipids

    OH-Chol is a cationic cholesterol derivative. It has been used in cationic nanoparticles in combination with Tween 80 ...

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    LNPTransfectionNanoparticlesiRNA delivery
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  • DOPE

    DOPE Image 1
    Synthetic lipids

    DOPE is a neutral phospholipid and displays sensitivity towards pH change and has been used in the preparation of lipo...

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    PhospholipidAmmoniumNanoparticleLiposomeTransfectionCationic lipidLipid
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  • ALC-0159

    ALC-0159 Image 1
    Synthetic lipids

    ALC-0159 is a lipid excipient. It has been deployed in the Pfizer-BioNTech SARS-CoV-2 mRNA vaccine in addition to ALC-...

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    ExcipientPegylatedAmmoniumNanoparticleLNPLiposomeTransfectionCationic lipid
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  • DOBAQ

    DOBAQ Image 1
    Synthetic lipids

    DOBAQ is a pH-sensitive lipid, which is cationic at pH= 4.0 It forms small, monodisperse liposomes with over 80% siRNA...

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    AmmoniumNanoparticleLNPLiposomeTransfectionCationic lipid
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  • DSPC

    DSPC Image 1
    Synthetic lipids

    DSPC has a relatively high main phase transition temperature (55.6 °C). It is commonly used in the generation of mice...

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    PhospholipidAmmoniumNanoparticleLNPLiposomeTransfectionCationic lipid
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  • 306Oi10

    306Oi10 Image 1
    Synthetic lipids

    306Oi10 is a biodegradable, branched chain lipidoid. 306Oi10 has been used to co-deliver three mRNAs (firefly luc...

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    mRNA deliveryNanoparticleLNPLiposomeTransfectionCationic lipid
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  • ALC-0315

    ALC-0315 Image 1
    Synthetic lipids

    ALC-0315 is one of the components in the BNT162b2 (Pfizer-Biontech) vaccine against SARS-CoV-2. Administration of (SAR...

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    mRNA deliveryNanoparticleLNPLiposomeTransfectionCationic lipid
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  • ATX-001

    ATX-001 Image 1
    Synthetic lipids

    ATX-001 and ATX-002 are lipids constructed from a SAR study to optimize physicochemical parameters resulting in good i...

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    Cationic lipidTransfectionLiposomeLNPNanoparticle
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  • ATX-002

    ATX-002 Image 1
    Synthetic lipids

    ATX-001 and ATX-002 are lipids constructed from an SAR study to optimize physicochemical parameters resulting in good ...

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    NanoparticleLNPLiposomeTransfectionCationic lipid
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